SBV Journal of Basic Clinical and Applied Health Science <p>SBV Journal of Basic, Clinical and Applied Health Science seeks to promote and disseminate the knowledge by publishing original research findings, review articles, empirical investigations, theoretical papers, case <em>studies</em> and short communications in the field of <em>health sciences</em> including anatomy, physiology, biochemistry, pharmacology, pathology, microbiology, social and preventive medicine; medicine, surgery, paediatrics, dentistry, nursing, obstetrics, gynaecology, pulmonary medicine, etc</p> <p>&nbsp;</p> Sri Balaji Vidyapeeth (Deemed University) en-US SBV Journal of Basic Clinical and Applied Health Science 2581-6039 Yoga is a Way of Life <p>The word “Yoga” has frmly entrenched itself in the global vocabulary. Majority believe yoga is valuable because it cures or prevents disease, making it a superb keep ft exercise. Others will only value its effectiveness in weight reduction. Some, a few, will concede that yoga practice bestows peace of mind and a feeling of well being, even of increased energy levels. No one will deny that Yoga does indeed produce all these good things. But! This is not and never has been the goal of Yoga. All these results are merely side benefts. The real purpose of Yoga was, is and shall always be Moksha, liberation, the achievement of the Highest Goal of Human Life, oneness with the Universal Self.</p> Ammaji Yogacharini Meenakshi Devi Bhavanani ##submission.copyrightStatement## 2018-06-30 2018-06-30 2 2 1 2 Addressing Autism Spectrum Disorder through Yoga as a Complementary Therapy <p>Autism is a neuro-developmental disorder characterized by restricted, repetitive activities and impaired social interaction. Its severity varies from individual to individual. Yoga, a mind–body intervention is often used as a complementary approach to enhance mental equipoise and focus and can be performed by all including those with acute or chronic painful disabilities. The emotional impact is difficult and devastating for people with autism and their families/caregivers. People with Autism Spectrum Disorder (ASD) should be regarded simply as ‘different’ rather than ‘disordered’; as they may have no speech or may have other complexities needing full-time care. Yogic techniques for ASD such as basic Jathis and Kriyas help to improve flexibility, Asanas work increase muscles and joints circulation and physical functioning becomes more integrated and less stressful. Pranayama and Asanas work hand-in-hand to balance and integrate different physiological functions, dissolve emotional blockages and negative habitual patterns. Yoga harmonises mind-body-emotion complex building up, helps to develop social relationships, promotes positive outlook, self-confidence and selfsufficiency. It also improves loco-motor skills, psycho-motor coordination, eye-hand coordination, attention span, immunity, appetite, sleep and promotes overall health. Regular practice reduces hyperactivity, aggression and dependency of drugs along with reduction in negative traits and tendencies to cause injury to self and others. In conclusion, yoga is an experiential science (Anubuthi Shastra) which can be used as a supplemental therapy for ASD.</p> Meena Ramanathan Ananda Balayogi Bhavanani ##submission.copyrightStatement## 2018-06-30 2018-06-30 2 2 3 7 An Insight on Selective Signaling Pathways Linking Obesity and Cancer <p>&nbsp;Obesity associated cancer is an important health issue. Major risk factors of obesity leading to cancer, through multiple signaling pathways, are insulin, insulin like growth factors, adipokines, and cytokines which are released from adipose tissue. The important signaling pathways are phosphoinositide 3-kinase (PI3K/ Akt), mitogen-activated protein kinase (MAPK) and signal transducer and activator of transcription 3 (STAT3). The PI3K/Akt and MAPK pathways have downstream effect on mammalian target of rapamycin (mTOR) leading to obesity associated cancer. Recent studies mostly focus on inhibition of mTOR for cancer therapy. It is essential to focus on PI3K/Akt, MAPK and STAT3 pathways which are under the impact of many cancer risk factors in obesity. Thus, signaling pathways may provide a novel approach for obesity associated cancer risk. In this review the signaling pathways linking obesity associated cancer are summarized.</p> Akshayavardhani A Pooja Pratheesh ##submission.copyrightStatement## 2018-06-30 2018-06-30 2 2 8 13 Efficacy of high-fidelity simulation in clinical problem solving exercises – feedback from teachers and learners <p><strong>Background &amp; Objectives</strong>: Simulation is one of the methods used to depict the symptoms and signs in clinical problem-solving exercises to medical students. The present study examined the efficacy of high-fidelity simulation in problem-solving exercises in preclinical medical education based on feedback from the lecturers and students. <br>Material and Methods: After approval from the research and ethics committee, 29 volunteers from year two in the school of Medicine, in AIMST University, Malaysia were recruited for the study. Two common problems in clinical medicine, chest pain, and breathlessness were selected. A pre-test was conducted for all the students on both topics. The teaching and learning of chest pain was conducted as a paper-based problem-solving exercise (PSE) while that of breathlessness was conducted as a problem-solving exercise using high-fidelity simulation. A post-test was conducted after both sessions. The lecturers and the students gave feedback on the efficacy of either method. <br><strong>Results</strong>: Ninety-three percent (25) of the students indicated a preference for simulation assisted PSE as compared to paper-based PSE. All the teachers felt that simulation assisted PSE is better in demonstrating signs and symptoms in a PSE for undergraduate medical students. The post-test scores of simulation assisted PSE were significantly higher than the paper-based PSE (p &lt; 0.0003). <br><strong>Conclusion</strong>: High-fidelity simulation assisted PSE was found to be more realistic and efficient than a paper-based PSE in portraying the clinical scenario in a problem-solving exercise in undergraduate medical education.</p> Gopalakrishnan Prabhakar Ponnusamy S Larmie E Soetjipto S Sethuraman KR ##submission.copyrightStatement## 2018-06-30 2018-06-30 2 2 14 22 Saline Nasal Douching Versus Decongestant Nasal Drops: A Comparative Study of Relative Efcacy in Post-Septal Surgery <p><strong>Background and Objective:</strong> This study aimed to compare the relative efficacy of saline nasal douches versus topical nasal decongestant in post-operative septal surgery and to assess the feasibility and likely utility in post-operative septal surgery. <br><strong>Material and Methods</strong>: The study was a hospital-based prospective double-blind randomized controlled study. Over a period of 18 months, 120 patients following septal surgery were assigned to one of two groups-Group I: Saline nasal douching and Group II: Decongestant nasal drops (xylometazoline 0.1 %). The outcome measures recorded on the 5th and 10th postoperative days are nasal congestion, anosmia, facial pain, itching, crusts, edema, scarring and nasal discharge. On the 14th postoperative day, the patients underwent diagnostic nasal endoscopic examination by the operating surgeon and the findings were recorded on the proforma. <br><strong>Results</strong>: On the 5th postoperative day, group I patients were found to be symptomatically better than group II and this trend continued upto the 10th postoperative day, with group I patients reporting better symptomatic outcomes. Examination of the nasal cavities showed statistically significant differences between the two groups in terms of crusts, edema and scarring. <br><strong>Conclusion</strong>: Saline nasal douching appears to provide better alleviation of post-septal surgery symptoms (anosmia, facial pain and itching) than nasal decongestants as experienced by the patient in terms of VAS scores. There was no difference in alleviating nasal decongestion between the 2 groups.</p> Karthikeyan P Pulimoottil DT Gopalakrishnan S ##submission.copyrightStatement## 2018-06-30 2018-06-30 2 2 23 27 Feasibility of a Design of an Objective Framework for Internal Assessment of Post Graduates in Prosthodontics <p><strong>Background and Objectives:</strong> Post Graduate Assessment in the Indian dental profession occurs only during the time of examination. There is no objective systematic record of evaluation conducted either in a formative or summative manner. Even if these records are present there is no weightage of internal assessment for evaluation of postgraduates. The study is intended to construct an objective framework with an appropriate curricular pattern for internal assessment for post graduates in prosthodontics specialty in dentistry. The model to be analysed for testing the feasibility of the model through an online focus group discussion involving the subject experts. <br><strong>Material and Methods:</strong> Situation analysis was carried out with feedback obtained from the trainees, trainers of the post graduate programme in prosthodontics. The proposed design was then subject to an online Focus Group Discussion involving subject experts at a senior level with more than 10 years of post-graduate training in the field all over India. <br><strong>Results:</strong> The inputs of the analysis was used to create a design of a curricular framework for post graduate prosthodontics and Crown &amp; Bridge training programme. This had the scope of systematic objective formative and summative evaluation in four modules – Pre-clinical, Basic clinical, Advanced clinical and Master clinical. The curriculum spacing and guidelines for assessment and scoring pattern was outlined. The outcomes of the Focus Group Discussion was analyzed by thematic analysis based on the lead questions and results were interpreted with a narrative description. <br><strong>Conclusion:</strong> The proposed tool was found to be feasible and acceptable with the minor modifications suggested from the focus group discussion.</p> Manoharan PS Sethuraman KR Narayan KA Adkoli BV ##submission.copyrightStatement## 2018-07-05 2018-07-05 2 2 28 35 Pattern of Utilization of Consultation-Liaison Psychiatry Services in A Tertiary Centre in South India <p><strong>Background and Objective</strong>: Consultation-Liaison Psychiatry (C-LP) services, an important aspect of every general hospital has wide variations in their pattern of services being utilized. Studies in this area are mostly conducted in northern states of India. Our study aims to see the pattern of inpatient referrals to the department of psychiatry in a tertiary hospital in South India. <br><strong>Material and Methods</strong>: One hundred and seventeen inpatient referrals to the Department of Psychiatry of a tertiary care hospital in Puducherry over a period of six months were included for the study. Informed consent was taken. Information about sociodemographic profiles was collected. Mini International Neuropsychiatric Interview (MINI-PLUS), a semi-structured diagnostic interview tool was administered for psychiatric diagnosis. <br><strong>Results</strong>: The inpatient referral rate was 1.50%. Evaluation of para-suicide was the commonest reason for referral (36.7%), followed by depressive symptoms (12.8%), alcohol related problems (12.8%), and abnormal behaviour (10.3%). Psychiatric diagnosis was found in 86% of cases referred; 41% had multiple psychiatric diagnoses. Deliberate Self-harm (DSH) was present in 28% and depressive disorder in 22% of cases. Gastro-intestinal disorders (12%), infectious disorders (11%) and cardiovascular disorders (9%) were the commonest medical diagnoses in the population. Department of Medicine had the highest referral rate; however referrals from most departments were very low. <br><strong>Conclusion:</strong> The study depicts a low referral rate which can be attributed to the lack of knowledge and high rate of stigma of psychiatric disorders. Thus, there is an urgent need to strengthen the existing C-LP services and screen for psychiatric disorders in non-psychiatric inpatients.</p> Jawahar Kennady Avudaiappan S Easwaran S Sukanto Sarkar ##submission.copyrightStatement## 2018-06-30 2018-06-30 2 2 36 41 Confidence Interval <p><span class="fontstyle0">Most of the research papers are strictly using a p-value to describe a significant&nbsp;value but omitting a confidence interval. Now a day, the publishers are demanding&nbsp;the effect size in terms of confidence interval which is more meaningful than a&nbsp;p-value. Introduction of the confidence interval in the research paper will limit the&nbsp;misinterpretation of p-values. This article will help the readers understand the&nbsp;importance of confidence interval while reporting a mean and standard deviation&nbsp;in their article.</span> </p> Ezhumalai G ##submission.copyrightStatement## 2018-06-30 2018-06-30 2 2 42 44 Staphylococcal Scalded Skin Syndrome Vs Toxic Epidermal Necrolysis <p>Staphylococcal Scalded Skin Syndrome (SSSS) and Toxic Epidermal Necrolysis (TEN) though rare are among the few emergencies in dermatology practice. Distinguishing between the two is vital for management. We report an 8-month-old baby with erythema and exfoliation of the skin. Certain subtle clinical clues helped to arrive at a correct diagnosis of Toxic Epidermal Necrolysis. This case exemplifies the need for a detailed history taking and astute clinical examination.</p> Ben Easow George Sreedevi Ambujam Gaddamanugu Sriteja ##submission.copyrightStatement## 2018-06-30 2018-06-30 2 2 45 47 A Case of Traumatic Optic Neuropathy Due to Lateral Compression <p><span class="fontstyle0">Traumatic optic neuropathy due to injury at the orbital apex is not uncommon. In this&nbsp;case report we present a case of traumatic optic neuropathy due to bony fragment&nbsp;of the lateral wall of the orbit impinging on the optic nerve which was successfully&nbsp;decompressed with open reduction and internal fixation.</span>&nbsp;&nbsp;</p> Ravikumar C Rajkamal Pandian D Vijay Nivas A Mathew Jackson I ##submission.copyrightStatement## 2018-06-30 2018-06-30 2 2 48 50